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2015
Rahimian, S., Kleinovink, J.W., Fransen, M.F., Mezzanotte, L., Gold, H., Wisse, P., Overkleeft, H., Amidi, M., Jiskoot, W., Lowik, C.W., Ossendorp, F., Hennink, W.E. , Near-infrared labeled, ovalbumin loaded polymeric nanoparticles based on a hydrophilic polyester as model vaccine: In vivo tracking and evaluation of antigen-specific CD8 T cell immune response, Biomaterials, vol. 37C, pp. 469-477. DOI
2012
Verheul, R.J., Hagenaars, N., van Es, T., van Gaal, E.V., de Jong, P.H., Bruijns, S., Mastrobattista, E., Slutter, B., Que, I, Heldens, J.G., van den Bosch, H., Glansbeek, H.L., Hennink, W.E., Jiskoot, W. , A step-by-step approach to study the influence of N-acetylation on the adjuvanticity of N,N,N-trimethyl chitosan (TMC) in an intranasal nanoparticulate influenza virus vaccine, Eur J Pharm Sci, vol. 45, issue 4, pp. 467-474. DOI
2011
Verheul, R.J., Slutter, B., Bal, S.M., Bouwstra, J.A., Jiskoot, W., Hennink, W.E. , Covalently stabilized trimethyl chitosan-hyaluronic acid nanoparticles for nasal and intradermal vaccination, J Contr Rel, vol. 156, issue 1, pp. 46-52. DOI
2010
van Hell, A.J., Klymchenko, A., Burgers, P.P., Moret, E.E., Jiskoot, W., Hennink, W.E., Crommelin, D.J.A., Mastrobattista, E. , Conformation and Intermolecular Interactions of SA2 Peptides Self-Assembled into Vesicles, Journal of Physical Chemistry B, vol. 114, no. 34, pp. 11046-11052. DOI
Amidi, M., Mastrobattista, E., Jiskoot, W., Hennink, W.E. , Chitosan-based delivery systems for protein therapeutics and antigens, Adv Drug Deliv Rev, vol. 62, no. 1, pp. 59-82. DOI
Slutter, B., Soema, P.C., Ding, Z., Verheul, R., Hennink, W., Jiskoot, W. , Conjugation of ovalbumin to trimethyl chitosan improves immunogenicity of the antigen, J Control Release, vol. 143, issue 2, pp. 207-214. DOI
2009
Rissmann, R., Oudshoorn, M.H., Hennink, W.E., Ponec, M., Bouwstra, J.A. , Skin barrier disruption by acetone: observations in a hairless mouse skin model, Arch Dermatol Res, vol. 301, no. 8, pp. 609-13. DOI
Rissmann, R., Oudshoorn, M.H.M., Zwier, R., Ponec, M., Bouwstra, J.A., Hennink, W.E. , Mimicking vernix caseosa-Preparation and characterization of synthetic biofilms, International Journal of Pharmaceutics, vol. 372, no. 1-2, pp. 59-65. DOI
Verheul, R.J., Amidi, M., van Steenbergen, M.J., van Riet, E., Jiskoot, W., Hennink, W.E. , Influence of the degree of acetylation on the enzymatic degradation and in vitro biological properties of trimethylated chitosans, Biomaterials, vol. 30, no. 18, pp. 3129-3135. DOI
Oudshoorn, M.H.M., Rissmann, R., Van der Coelen, D., Hennink, W.E., Ponec, M., Bouwstra, J.A. , Development of a murine model to evaluate the effect of vernix caseosa on skin barrier recovery, Experimental Dermatology, vol. 18, no. 2, pp. 178-184. DOI
Ghassemi, A.H., van Steenbergen, M.J., Talsma, H., van Nostrum, C.F., Jiskoot, W., Crommelin, D.J.A., Hennink, W.E. , Preparation and characterization of protein loaded microspheres based on a hydroxylated aliphatic polyester, poly (lactic-co-hydroxymethyl glycolic acid), Journal of Controlled Release, vol. 138, no. 1, pp. 57-63. DOI
Oudshoorn, M.H.M., Rissmann, R., van der Coelen, D., Hennink, W.E., Ponec, M., Bouwstra, J.A. , Effect of synthetic vernix biofilms on barrier recovery of damaged mouse skin, Experimental Dermatology, vol. 18, no. 8, pp. 695-703. DOI
2008
Verheul, R.J., Amidi, M., van der Wal, S., van Riet, E., Jiskoot, W., Hennink, W.E. , Synthesis, characterization and in vitro biological properties of O-methyl free N,N,N-trimethylated chitosan, Biomaterials, vol. 29, no. 27, pp. 3642-3649. DOI
Rissmann, R., Oudshoorn, M.H.M., Kocks, E., Hennink, W.E., Ponec, M., Bouwstra, J.A. , Lanolin-derived lipid mixtures mimic closely the lipid composition and organization of vernix caseosa lipids, Biochimica Et Biophysica Acta-Biomembranes, vol. 1778, no. 10, pp. 2350-2360. DOI
Amidi, M., Krudys, K.M., Snel, C.J., Crommelin, D.J.A., Della Pasqua, O.E., Hennink, W.E., Jiskoot, W. , Efficacy of pulmonary insulin delivery in diabetic rats: Use of a model-based approach in the evaluation of insulin powder formulations, Journal of Controlled Release, vol. 127, no. 3, pp. 257-266. DOI
Amidi, M., Pellikaan, H.C., de Boer, A.H., Crommelin, D.J.A., Hennink, W.E., Jiskoot, W. , Preparation and physicochemical characterization of supercritically dried insulin-loaded microparticles for pulmonary delivery, European Journal of Pharmaceutics and Biopharmaceutics, vol. 68, no. 2, pp. 191-200. DOI
Rissmann, R., Groenink, H.W.W., Gooris, G.S., Oudshoorn, M.H.M., Hennink, W.E., Ponec, M., Bouwstra, J.A. , Temperature-induced changes in structural and physicochemical properties of vernix caseosa, Journal of Investigative Dermatology, vol. 128, no. 2, pp. 292-299. DOI
2007
Metz, B., Jiskoot, W., Mekkes, D., Kingma, R., Hennink, W.E., Crommelin, D.J.A., Kersten, G.E.A. , Quality control of routine, experimental and real-time aged diphtheria toxoids by in vitro analytical techniques, Vaccine, vol. 25, no. 39-40, pp. 6863-6871. DOI
Amidi, M., Pellikaan, H.C., Hirschberg, H., de Boerd, A.H., Crommelin, D.J.A., Hennink, W.E., Kersten, G., Jiskoot, W. , Diphtheria toxoid-containing microparticulate powder formulations for pulmonary vaccination: Preparation, characterization and evaluation in guinea pigs, Vaccine, vol. 25, no. 37-38, pp. 6818-6829. DOI
van Hell, A.J., Costa, C.I.C.A., Flesch, F.M., Sutter, M., Jiskoot, W., Crommelin, D.J.A., Hennink, W.E., Mastrobattista, E. , Self-assembly of recombinant amphiphilic oligopeptides into vesicles, Biomacromolecules, vol. 8, no. 9, pp. 2753-2761. DOI
Oudshoorn, M.H.M., Penterman, R., Rissmann, R., Bouwstra, J.A., Broer, D.J., Hennink, W.E. , Preparation and characterization of structured hydrogel microparticles based on cross-linked hyperbranched polyglycerol, Langmuir, vol. 23, no. 23, pp. 11819-11825. DOI
Vlugt-Wensink, K.D.F., Meijer, Y.J., van Steenbergen, M.J., Verrijk, R., Jiskoot, W., Crommelin, D.J.A., Hennink, W.E. , Effect of excipeients on the encapsulation efficiency and release of human growth hormone from dextran microspheres, European Journal of Pharmaceutics and Biopharmaceutics, vol. 67, no. 3, pp. 589-596. DOI
Oudshoorn, M.H.M., Rissmann, R., Bouwstra, J.A., Hennink, W.E. , Synthesis of methacrylated hyaluronic acid with tailored degree of substitution, Polymer, vol. 48, no. 7, pp. 1915-1920. DOI
Sutter, M., Oliveira, S., Sanders, N.N., Lucas, B., van Hoek, A., Hink, M.A., Visser, A.J.W.G., De Smedt, S.C., Hennink, W.E., Jiskoot, W. , Sensitive spectroscopic detection of large and denatured protein aggregates in solution by use of the fluorescent dye Nile red, Journal of Fluorescence, vol. 17, no. 2, pp. 181-192. DOI
Sutter, M., Siepmann, J., Hennink, W.E., Jiskoot, W. , Recombinant gelatin hydrogels for the sustained release of proteins, Journal of Controlled Release, vol. 119, no. 3, pp. 301-312. DOI
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