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2014
Nuchuchua, O., Every, H.A., Hofland, G.W., Jiskoot, W. , Scalable organic solvent free supercritical fluid spray drying process for producing dry protein formulations, Eur J Pharm Biopharm, vol. 88, no. 3, pp. 919-30. DOI
2008
Bouchard, A., Jovanovic, N., de Boer, A.H., Martin, A., Jiskoot, W., Crommelin, D.J.A., Hofland, G.W., Witkamp, G.J. , Effect of the spraying conditions and nozzle design on the shape and size distribution of particles obtained with supercritical fluid drying, European Journal of Pharmaceutics and Biopharmaceutics, vol. 70, no. 1, pp. 389-401. DOI
Bouchard, A., Jovanovic, N., Hofland, G.W., Jiskoot, W., Mendes, E., Crommelin, D.J.A., Witkamp, G.J. , Supercritical fluid drying of carbohydrates: Selection of suitable excipients and process conditions, European Journal of Pharmaceutics and Biopharmaceutics, vol. 68, no. 3, pp. 781-794.
Jovanovic, N., Bouchard, A., Sutter, M., Van Speybroeck, M., Hofland, G.W., Witkamp, G.J., Crommelin, D.J.A., Jiskoot, W. , Stable sugar-based protein formulations by supercritical fluid drying, International Journal of Pharmaceutics, vol. 346, no. 1-2, pp. 102-108. DOI
Jovanovic, N., Bouchard, A., Hofland, G.W., Witkamp, G.J., Crommelin, D.J.A., Jiskoot, W. , Stabilization of IgG by supercritical fluid drying: Optimization of formulation and process parameters, European Journal of Pharmaceutics and Biopharmaceutics, vol. 68, no. 2, pp. 183-190. DOI
Bouchard, A., Jovanovic, N., Martin, A., Hofland, G.W., Crommelin, D.J.A., Jiskoot, W., Witkamp, G.J. , Effect of the modifier on the particle formation and crystallisation behaviour during precipitation from aqueous solutions, Journal of Supercritical Fluids, vol. 44, no. 3, pp. 409-421. DOI
Bouchard, A., Jovanovic, N., Hofland, G.W., Crommelin, D.J.A., Jiskoot, W., Witkamp, G.J. , Ways of manipulating the polymorphism of glycine during supercritical fluid crystallisation, Journal of Supercritical Fluids, vol. 44, no. 3, pp. 422-432. DOI
2007
Bouchard, A., Jovanovic, N., Jiskoot, W., Mendes, E., Witkamp, G.J., Crommelin, D.J.A., Hofland, G.W. , Lysozyme particle formation during supercritical fluid drying: Particle morphology and molecular integrity, Journal of Supercritical Fluids, vol. 40, no. 2, pp. 293-307. DOI
Bouchard, A., Jovanovic, N., Hofland, G.W., Mendes, E., Crommelin, D.J.A., Jiskoot, W., Witkamp, G.J. , Selective production of polymorphs and pseudomorphs using supercritical fluid crystallization from aqueous solutions, Crystal Growth & Design, vol. 7, no. 8, pp. 1432-1440. DOI
2006
Jovanovic, N., Bouchard, A., Hofland, G.W., Witkamp, G.J., Crommelin, D.J.A., Jiskoot, W. , Distinct effects of sucrose and trehalose on protein stability during supercritical fluid drying and freeze-drying, European Journal of Pharmaceutical Sciences, vol. 27, no. 4, pp. 336-345. DOI
2004
Jovanovic, N., Bouchard, A., Hofland, G.W., Witkamp, G.J., Crommelin, D.J.A., Jiskoot, W. , Stabilization of proteins in dry powder formulations using supercritical fluid technology, Pharmaceutical Research, vol. 21, no. 11, pp. 1955-1969.
1997
Bouwstra, J.A., vanHal, D.A., Hofland, H.E.J., Junginger, H.E. , Preparation and characterization of nonionic surfactant vesicles, Colloids and Surfaces a-Physicochemical and Engineering Aspects, vol. 123, pp. 71-80.
1995
Hofland, H.E.J., Bouwstra, J.A., Bodde, H.E., Spies, F., Junginger, H.E. , Interactions between Liposomes and Human Stratum-Corneum in-Vitro - Freeze-Fracture Electron-Microscopic Visualization and Small-Angle X-Ray-Scattering Studies, British Journal of Dermatology, vol. 132, no. 6, pp. 853-866.
1994
Hofland, H.E.J., Vandergeest, R., Bodde, H.E., Junginger, H.E., Bouwstra, J.A. , Estradiol Permeation from Nonionic Surfactant Vesicles through Human Stratum-Corneum in-Vitro, Pharmaceutical Research, vol. 11, no. 5, pp. 659-664.
1993
Hofland, H.E.J., Bouwstra, J.A., Gooris, G.S., Spies, F., Talsma, H., Junginger, H.E. , Nonionic Surfactant Vesicles - a Study of Vesicle Formation, Characterization, and Stability, Journal of Colloid and Interface Science, vol. 161, no. 2, pp. 366-376.
1992
Buckton, G., Chowdhry, B.Z., Armstrong, J.K., Leharne, S.A., Bouwstra, J.A., Hofland, H.E.J. , The Use of High-Sensitivity Differential Scanning Calorimetry to Characterize Dilute Aqueous Dispersions of Surfactants, International Journal of Pharmaceutics, vol. 83, no. 1-3, pp. 115-121.
Hofland, H.E.J., Bouwstra, J.A., Verhoef, J.C., Buckton, G., Chowdry, B.Z., Ponec, M., Junginger, H.E. , Safety Aspects of Nonionic Surfactant Vesicles - a Toxicity Study Related to the Physicochemical Characteristics of Nonionic Surfactants, Journal of Pharmacy and Pharmacology, vol. 44, no. 4, pp. 287-294.
1991
Hofland, H.E.J., Bouwstra, J.A., Ponec, M., Bodde, H.E., Spies, F., Verhoef, J.C., Junginger, H.E. , Interactions of Nonionic Surfactant Vesicles with Cultured Keratinocytes and Human Skin Invitro - a Survey of Toxicological Aspects and Ultrastructural-Changes in Stratum-Corneum, Journal of Controlled Release, vol. 16, no. 1-2, pp. 155-167.
1988
Hofland, H.E.J., Bouwstra, J.A., Talsma, H., Spies, F., Junginger, H.E. , Characterization of Non-Ionic Surfactant Vesicles - Structure, Size and Stability, Pharmaceutisch Weekblad-Scientific Edition, vol. 10, no. 2, pp. 98-98.