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2014
Torosantucci, R., Schoneich, C., Jiskoot, W. , Oxidation of Therapeutic Proteins and Peptides: Structural and Biological Consequences, Pharmaceutical research, vol. 31, pp. 541-553. DOI
Torosantucci, R., Brinks, V., Kijanka, G., Halim, L.A., Sauerborn, M., Schellekens, H., Jiskoot, W. , Development of a Transgenic Mouse Model to Study the Immunogenicity of Recombinant Human Insulin, Journal of pharmaceutical sciences, vol. 103, issue 5, pp. 1367–1374. DOI
2013
Torosantucci, R., Sharov, V.S., van Beers, M., Brinks, V., Schoneich, C., Jiskoot, W. , Identification of Oxidation Sites and Covalent Cross-Links in Metal Catalyzed Oxidized Interferon Beta-1a: Potential Implications for Protein Aggregation and Immunogenicity, Molecular pharmaceutics, vol. 10, issue 6, pp. 2311–2322. DOI
Torosantucci, R., Weinbuch, D., Klem, R., Jiskoot, W. , Triethylenetetramine prevents insulin aggregation and fragmentation during copper catalyzed oxidation, Eur J of Pharm and Biopharm, vol. 84, issue 3, pp. 464–471. DOI
2012
2011
Torosantucci, R., Kukrer, B., Mero, A., Winsen, M.V., Tantipolphan, R., Jiskoot, W. , Plain and mono-pegylated recombinant human insulin exhibit similar stress-induced aggregation profiles, J Pharm Sci, vol. 100, issue 7, pp. 2574-2585. DOI
2010
Tantipolphan, R., Romeijn, S., Engelsman, J., Torosantucci, R., Rasmussen, T., Jiskoot, W. , Elution behavior of insulin on high-performance size exclusion chromatography at neutral pH, J Pharm Biomed Anal, vol. 52, no. 2, pp. 195-202. DOI